Ask The Supp Guru: Does Whey Lower Testosterone Levels?


Q: I have been instructed that consuming protein lowers testosterone, however this appears considerably counterintuitive. Ought to I actually skip the shake within the identify of my T-levels?

Protein reducing your testosterone ranges is an previous concern that’s grounded in good science. Nevertheless, newer analysis provides a distinct image, and factors to an enchanting risk. So, let’s break down each viewpoints.

Circulating ranges of testosterone quickly improve everytime you prepare with excessive depth and quantity. It does not matter in case you’re male or feminine, simply that you simply push your self. And sure, that improve in testosterone from weight coaching alone has typically been proven to be diminished or blunted in case you devour protein previous to or instantly after your exercise.[1,2] However, not at all times.[3]

Additional muddying the waters, different research have additionally reported that high-protein diets decrease resting ranges of circulating testosterone, whereas others have proven that rising protein can improve testosterone availability.[4,5]

So, which is it? Does protein improve or lower your testosterone? A speculation raised inside a 2008 paper raises the concept that it isn’t an both/or proposition.[6]

What if protein—or particular varieties of protein—trigger each a rise in whole testosterone, and a reducing of circulating ranges of testosterone? Not as a result of the protein is decreasing your manufacturing of testosterone, however as a result of extra circulating testosterone is being faraway from the bloodstream and truly coming into cells the place it may well have an effect on cell operate?

Does Whey Raise Testosterone Levels?

In different phrases, what if sure proteins—or one thing in these proteins—can amplify the training-induced rise within the sensitivity of androgen receptors, these mobile ports that shuttle testosterone into cells and permit it to do its essential work?

For one factor, it will imply that blood samples that solely assess a snapshot of the quantity of testosterone circulating exterior of tissues (extracellular) would solely be telling us a bit of the entire story. However, it will additionally imply that protein is critically highly effective stuff.

Move the Take a look at with Flying Colours

Unpublished analysis out of the Molecular and Utilized Sciences Laboratory at Auburn College might flip all the pieces we thought we knew about testosterone, in addition to how testosterone itself is measured, on its head.[7]

Now to be clear, the brand new analysis I am referring to was accomplished in rodents, however it dovetails with analysis carried out on people and offers tantalizing prospects for additional human-focused analysis. The experiment required that the rats carry out repeated muscle contractions to simulate 4 units of a one-legged calf increase motion. Instantly after this “coaching”, the rats acquired both 500 milligrams of whey protein, which offered roughly 50 milligrams of leucine, or the rats got simply a further 54 milligrams of leucine, or water solely (the management group). When extrapolated to people, that is about 19 grams of whey protein and a couple of.eight grams of leucine—each fairly normal doses. Blood and muscle samples had been assessed at three hours post-supplementation.

This is what the researchers discovered: Supplementing with whey resulted in a 90.5-percent improve within the intracellular focus of testosterone current inside the exercised muscle, over the non-exercised muscle. Leucine alone, then again, induced a mean, however non-significant discount in intracellular testosterone. In truth, whey raised intracellular ranges of testosterone by 150 % greater than leucine alone inside exercised muscle.

Does Whey Raise Testosterone Levels?

Such findings appear to assist the developments noticed by researchers within the 2008 paper, once they reported a rise within the manufacturing of androgen receptors inside exercised muscle mass in response to whey, at one and 48 hours post-exercise.[6]

Whereas additional analysis must be accomplished, it raises some fascinating prospects. For instance, if whey will increase the uptake of testosterone from the blood and into exercised muscle mass, then the elevated concentrations of testosterone current intracellularly might stimulate the manufacturing of extra androgen receptors. Over time, having extra androgen receptors would proceed to repay. It might make the muscle extra delicate to the presence of androgens and possibly require much less protein and assist you to make extra of each little bit of free testosterone you have got.

If that is true, then the query of whether or not whey is really anabolic or pro-testosterone can be an unequivocal sure!

The truth that whey produced this response, however leucine alone didn’t, can be important. Whereas free amino acids like leucine have their advantages, this research factors to the potential to provide new discoveries concerning the particular worth of whey protein. Particularly, there could also be bioactive peptides current inside whey protein, however not leucine, that make whey a superior alternative for post-workout diet and muscle-building.

Extra analysis must be accomplished, however for now, positively do not skip that shake out of concern that your take a look at ranges will take a success. The other may very well be occurring!

  1. Hulmi, J. J., Volek, J. S., SelÄnne, H., & Mero, A. A. (2005). Protein ingestion previous to energy train impacts blood hormones and metabolism. Drugs & Science in Sports activities & Train, 37(11), 1990-1997.
  2. Hulmi, J. J., Ahtiainen, J. P., Selänne, H., Volek, J. S., Häkkinen, Ok., Kovanen, V., & Mero, A. A. (2008). Androgen receptors and testosterone in males—results of protein ingestion, resistance train and fiber sort. The Journal of Steroid Biochemistry and Molecular Biology, 110(1-2), 130-137.
  3. Kraemer, W. J., Solomon-Hill, G., Volk, B. M., Kupchak, B. R., Looney, D. P., Dunn-Lewis, C., … & Maresh, C. M. (2013). The results of soy and whey protein supplementation on acute hormonal responses to resistance train in males. Journal of the American Faculty of Diet, 32(1), 66-74.
  4. Anderson, Ok. E., Rosner, W., Khan, M. S., New, M. I., Pang, S., Wissel, P. S., & Kappas, A. (1987). Weight loss plan-hormone interactions: protein/carbohydrate ratio alters reciprocally the plasma ranges of testosterone and cortisol and their respective binding globulins in man. Life Sciences, 40(18), 1761-1768.
  5. Remer, T. (2001). Dietary protein and fiber consumption and intercourse hormone-binding globulin. The Journal of Scientific Endocrinology and Metabolism, 86(2), 950.
  6. Hulmi, J. J., Ahtiainen, J. P., Selänne, H., Volek, J. S., Häkkinen, Ok., Kovanen, V., & Mero, A. A. (2008). Androgen receptors and testosterone in males—results of protein ingestion, resistance train and fiber sort. The Journal of Steroid Biochemistry and Molecular Biology, 110(1-2), 130-137.
  7. Unpublished information from PMID 26507545, introduced by Lockwood CM, Roberts MD, Wilson J and Wilson G. Diet and muscle positive aspects – Does leucine content material matter: A Level-Counterpoint Debate. 12th Annual ISSN Convention and Expo, Austin, TX. June 12, 2015.